標題PSMB8 antibody Catalog Number：OM272721

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/9/27 閱讀次數：48次 >>進入該公司展臺

Product Name	PSMB8 antibody
Antibody Type	Primary Antibodies
Product description	Rabbit Polyclonal antibody to PSMB8The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits ａnd 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration ａnd cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon ａnd this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative t More
Immunogen	Recombinant protein of human PSMB8

Gene Synonyms	D6S216E RING10 ALDD LMP7 D6S216 JMP proteasome subunit beta 8 PSMB5i NKJO More
Target	PSMB8

Application

Western blot analysis of extracts of various cell lines, using PSMB8 antibody.
Application

Immunohistochemistry of paraffin-embedded rat heart using PSMB8 antibody at dilution of 1:100 (x400 lens).
Application

Immunohistochemistry of paraffin-embedded human colon using PSMB8 antibody at dilution of 1:100 (x400 lens).
Application

Immunohistochemistry of paraffin-embedded human kidney using PSMB8 antibody at dilution of 1:100 (x400 lens).
Application

Immunofluorescence analysis of A549 cell using PSMB8 antibody. Blue: DAPI for nuclear staining.