標題MCM7 antibody Catalog Number：OM262670

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/9/27 閱讀次數(shù)：38次 >>進入該公司展臺

Product Name	MCM7 antibody
Antibody Type	Primary Antibodies
Product description	Rabbit Polyclonal antibody to MCM7The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) ａnd may be involved in the formation of replication forks ａnd in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein ａnd MCM2, 4 ａnd 6 proteins possesses DNA helicase activity, ａnd may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, ａnd may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] More
Immunogen	Recombinant protein of human MCM7

Gene Synonyms	minichromosome maintenance complex component 7 P1.1-MCM3 P1CDC47 PNAS146 P85MCM CDC47 MCM2 More
Target	MCM7
Molecular Weight(MW)	81 kDa (note)

Application

WB analysis of extracts from various cells using MCM7 antibody.
Application

IHC-P analysis of human breast cancer using MCM7 antibody at a dilution of 1:200.
Application

IHC-P analysis of human esophageal cancer using MCM7 antibody at a dilution of 1:200.
Application

IHC-P analysis of human rectal cancer using MCM7 antibody at a dilution of 1:200.
Application

IHC-P analysis of rat brain using MCM7 antibody at a dilution of 1:200.
Application

ICC/IF analysis of HeLa cells using MCM7 antibody (green) ａnd DAPI (blue).

Application Notes	WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:

Form	Liquid
Storage Instructions	Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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