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您的位置：首頁 > 技術(shù)文獻(xiàn) > 產(chǎn)品說明 > FGG Antibody Catalog Number：OM278837

標(biāo)題FGG Antibody Catalog Number：OM278837

   

提供者：上海篤瑪生物科技有限公司    發(fā)布時間：2024/9/19   閱讀次數(shù)：23次 >>進(jìn)入該公司展臺
 

Product Profile

Product Name FGG Antibody
Antibody Type Primary Antibodies
Product description 
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia.The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.1) Uitte (2006) J. Thromb. Haemost. 4 (2), 474-476.
More 
Immunogen 
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGG.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAWB
 
FGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 μg/mL, ａnd HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

DogHumanMouseRat
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol FGG
Alternative Names
FGG
Molecular Weight(MW) 46 kDa, 52 kDa

Database Links

Entrez Gene 2266
Protein Accession NP_000500

Application

  • Application

    Antibody used in WB on Human Liver at 2.5 ug/ml.

Positive Control 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Application Notes
FGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 μg/mL, ａnd HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store FGG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

關(guān)鍵詞：穩(wěn)定性強  特異性強    靈敏度高  

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