標(biāo)題HLA-G antibody Catalog Number：OM257151

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/9/30 閱讀次數(shù)：69次 >>進(jìn)入該公司展臺

Product Name	HLA-G antibody
Antibody Type	Primary Antibodies
Product description	Mouse monoclonal [MEM - G / 1] to HLA GHLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain ａnd a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa ａnd its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 ａnd 3 encode the alpha1 ａnd alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, ａnd exon 6 encodes the cylasmic tail. [provided by RefSeq] More
Immunogen	Recombinant full length denatured heavy chain (Human).

Clonality	Monoclonal
Isotype	IgG1
Clone Number	MEM-G/1
Host Species	Mouse
Tested Applications	IHCIHC-PWB
	IHC-P: Use at an assay dependant dilution. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. WB: Use at an assay dependant dilution. Does not react with native HLA-G on cell surface. Optimal dilutions/concentrations should be determined by the end user.: More
Species Reactivity	Human
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification	Affinity purified

Gene Synonyms	HLA G HLAG MHC-G MHC G MHCG More
Target	HLA-G
Tissue Specificity	The antibody reacts with denaturated HLA-G heavy chain.
Cellular Localization	Cell Membrane

Application

Immunohistochemistry staining with anti-human HLA-G (MEM-G/1) . Fig. 1B - first-trimester placenta (paraffin-embedded sections)
Application

The antibody stains infiltrating macrophages in pulmonary diseases. In the left corner see detail of macropage.

Application Notes	IHC-P: Use at an assay dependant dilution. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. WB: Use at an assay dependant dilution. Does not react with native HLA-G on cell surface. Optimal dilutions/concentrations should be determined by the end user.: More

Form	Liquid
Storage Instructions	Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot ａnd store at -20ºC or below. Avoid freeze-thaw cycles.
Storage Buffer	Phosphate buffered saline pH 7.4 containing 15mM sodium azide

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