標(biāo)題SUMO2/3 Antibody Catalog Number：OM292543

提供者：上海篤瑪生物科技有限公司發(fā)布時(shí)間：2024/9/30 閱讀次數(shù)：50次 >>進(jìn)入該公司展臺(tái)

Product Name	SUMO2/3 Antibody
Antibody Type	Primary Antibodies
Product description	SUMO2/3 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (Sumo-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, which is a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis ａnd protein stability. All SUMO proteins localize to the nucleus ａnd are covalently conjugated, affecting protein structure, function ａnd interactions. SUMO2 ａnd 3 are 96% identical ａnd are more mobile within nucleus relative to SUMO1. Specific functional differences between SUMO1 ａnd SUMO2 ａnd 3 remain to be identified.1) Kamitani T, Kito K, Nguyen HP, et al. Characterization of a second member of the sentrin family of ubiquitin-like proteins. J. Biol. Chem.1998;273:11349-53. More
Immunogen	SUMO2/3 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SUMO2. The immunogen is located within the last 50 amino acids of SUMO2/3.

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	ELISAIFIHC-PWB
	SUMO2/3 antibody can be used for detection of SUMO2 ａnd SUMO3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Affinity purified

Gene Symbol	SUMO2
Alternative Names	SUMO2/3 Antibody: HSMT3 SMT3B SUMO3 Smt3A SMT3H2 SMT3A Small ubiquitin-related modifier 2 HSMT3 SUMO-2 More
Molecular Weight(MW)	Predicted: 15 kDa Observed: 15 kDa
Sequence Similarities	Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (93%), Pig: (93%)

Entrez Gene	6613
Protein Accession	AAH71645

Application

Western blot analysis of SUMO2/3 in Jurkat cell lysate with SUMO2/3 antibody at (A) 1 ａnd (B) 2 μg/mL.
Application

Immunofluorescence of SUMO2/3 in rat liver tissue with SUMO2/3 antibody at 20 μg/mL.
Application

Immunohistochemistry of SUMO2/3 in rat liver tissue with SUMO2/3 antibody at 5 μg/mL.

Positive Control	1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes	SUMO2/3 antibody can be used for detection of SUMO2 ａnd SUMO3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.:

Form	Liquid
Storage Instructions	SUMO2/3 antibody can be stored at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer	SUMO2/3 Antibody is supplied in PBS containing 0.02% sodium azide.

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