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您的位置:首頁(yè) > 技術(shù)文獻(xiàn) > 產(chǎn)品說(shuō)明 > PPP1CA [B11-E9] Catalog Number:OM627686

標(biāo)題PPP1CA [B11-E9] Catalog Number:OM627686

   

提供者:上海篤瑪生物科技有限公司    發(fā)布時(shí)間:2024/9/24   閱讀次數(shù):31次 >>進(jìn)入該公司展臺(tái)
 

Product Profile

Product Name PPP1CA [B11-E9]
Antibody Type Primary Antibodies
Product description
In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP1 family is comprised of subfamily members PP1α, PP1β and PP1γ, which are MgATP-dependent enzymes. PP1 inactivity is maintained through its association with the inhibitory protein NIPP-1 (nuclear inhibitor of PP1). Phosphorylation of NIPP-1 by cAMP-PK or casein kinase II results in the release of active PP1.
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Immunogen
Recombinant protein

Key Feature

Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications

WB

 
WB:1:500
Species Reactivity

Human

Concentration 2 mg/mL.

Target Information

Alternative Names
Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit antibody Catalytic subunit antibody EC 3.1.3.16 antibody MGC15877 antibody MGC1674 antibody PP 1A antibody PP-1A antibody PP1A antibody PP1A_HUMAN antibody PP1alpha antibody PP2C ALPHA antibody PP2CA antibody Ppp1ca antibody Protein Phosphatase 2C Alpha Isoform antibody Serine threonine protein phosphatase PP1 alpha catalytic subunit antibody Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1 antibody Serine/threonine-protein phosphatase PP1-alpha catalytic subunit antibody
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Molecular Weight(MW) 38 kDa
Cellular Localization Nucleus. Cylasm.

Database Links

SwissProt ID P62136

Application

  • Application

    Fig1: Western blot analysis of PPP1CA on human PPP1CA recombinant protein using anti-PPP1CA antibody at 1/1,000 dilution.

  • Application

    Fig2: Western blot analysis of PPP1CA on different cell lysates using anti-PPP1CA antibody at 1/1,000 dilution. Positive control: Lane 1: A431 Lane 2: Hela Lane 3: HepG2 Lane 4: CF-7 Lane 5:Jurkat? Lane 6: A549

Positive Control Human PPP1CA recombinant protein, A431, Hela, HepG2, MCF-7, Jurkat, A549.
Application Notes
WB:1:500

Additional Information

Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

關(guān)鍵詞:穩(wěn)定性強(qiáng)  特異性強(qiáng)    靈敏度高  

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