標(biāo)題DLK1 [D2-A3] Catalog Number：OM627678

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/9/23 閱讀次數(shù)：34次 >>進(jìn)入該公司展臺

Product Name	DLK1 [D2-A3]
Antibody Type	Primary Antibodies
Product description	The DLK1 protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on ｃhr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal ａnd paternal uniparental disomy of chromosome 14 (UPD14). This proteins＇ gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child ａnd adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy ａnd decreased fat mass. More
Immunogen	Recombinant protein

Alternative Names	Adipocyte differentiation inhibitor protein antibody Brevideltin antibody Delta like 1 homolog antibody Delta like homolog antibody Delta like protein antibody Delta1 antibody DLK 1 antibody DLK antibody DLK-1 antibody DLK1 antibody DLK1_HUMAN antibody FA 1 antibody FA1 antibody Fetal antigen 1 antibody pG2 antibody Preadipocyte factor 1 antibody Pref 1 antibody Pref antibody Pref1 antibody Protein delta homolog 1 antibody Secredeltin antibody ZOG antibody More
Molecular Weight(MW)	41 kDa
Cellular Localization	Membrane.

SwissProt ID	P80370 Q09163

Application

Fig1: Western blot analysis of DLK1 on human DLK1 recombinant protein using anti-DLK1 antibody at 1/1,000 dilution.
Application

Fig2: ICC staining DLK1 (green) ａnd actin filaments (red) in U251 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application

Fig3:Flow cytometric analysis of NIH/3T3 cells with DLK1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

Positive Control	Human DLK1 recombinant protein, U251, NIH/3T3.
Application Notes	WB:1:500-1:1,000 ICC:1:50-1:200 FC:1:100-1:200

Form	Liquid
Storage Instructions	Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer	1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

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