標(biāo)題Bmi1 Antibody Catalog Number：OM214005

提供者：上海篤瑪生物科技有限公司發(fā)布時(shí)間：2024/9/20 閱讀次數(shù)：49次 >>進(jìn)入該公司展臺(tái)

Product Name	Bmi1 Antibody
Antibody Type	Primary Antibodies

Gene Synonyms	Bmi-1 Pcgf4
Alternative Names	Bmi1 Bmi-1 Pcgf4 Polycomb complex protein BMI-1 Polycomb group RING finger protein 4 More
Molecular Weight(MW)	36708 Da
Function	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling ａnd modification of histones; it mediates monoubiquitination of histone H2A ＇Lys-119＇, rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity) More
Tissue Specificity	Detected in most organs with high expression levels in thymus, heart, brain ａnd testis
Cellular Localization	Nucleus. Cylasm (By similarity).

Entrez Gene	12151
Nucleotide Accession	NP_031578.2

Application

Mouse Bmi1 antibody (Cat. #AM1980b) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Mouse Bmi1 antibody detected the Mouse Bmi1 protein (arrow).

Application Notes	WB~~1:200~1600:

Form	Liquid
Storage Instructions	For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

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