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Product Name | Rabbit anti-FGG polyclonal antibody - middle region |
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Antibody Type | Primary Antibodies |
Immunogen | The immunogen for anti-FGG antibody: synthetic peptide directed towards the middle region of human FGG |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | WB |
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
Species Reactivity | BovineDogHorseHumanMousePigRabbitZebra Fish |
Concentration | 1 mg/ml |
Purification | Affinity purified |
Gene Symbol | FGG |
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Gene Synonyms | |
Gene Full Name | Fibrinogen gamma chain |
Gene Summary | FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. More |
Molecular Weight(MW) | 46kDa |
Sequence | 437 amino acids |
Entrez Gene | 2266 |
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SwissProt ID | P02679 |
Protein Accession | NP_000500 |
Immunohistochemistry with Placenta tissue
0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysate
Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
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Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
關(guān)鍵詞:穩(wěn)定性強(qiáng) 特異性強(qiáng) 靈敏度高
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