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您的位置:首頁 > 技術文獻 > 產(chǎn)品說明 > Anti-WHSC2 antibody Catalog Number:OM642659

標題Anti-WHSC2 antibody Catalog Number:OM642659

   

提供者:上海篤瑪生物科技有限公司    發(fā)布時間:2024/9/2   閱讀次數(shù):23次 >>進入該公司展臺
 

Product Profile

Product Name Anti-WHSC2 antibody
Antibody Type Primary Antibodies
Immunogen
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIHCWB

 
WB:1:200-1:2000
IHC:1:200-1:2000
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Protein A

Target Information

Gene Symbol NELFA
Gene Synonyms
WHSC2
NELF-A
P/OKcl.15
Gene Full Name negative elongation factor complex member A
Gene Summary
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
More 
Molecular Weight(MW) 57KD
Cellular Localization Nucleus

Application

  • WB

    Western blot analysis using WHSC2 antibody against A549(1) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using WHSC2 antibody with DAB staining.

  • IHC

    Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using WHSC2 antibody with DAB staining.

Application Notes
WB:1:200-1:2000
IHC:1:200-1:2000

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.

關鍵詞:Product  Profile  Product  NameAnti-WHSC2  antibody  Antibody  TypePrimary  Antibodies  Immunogen  Polype  

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