標(biāo)題PI3K p85/p55 (phospho Tyr467/199) antibody Catalog Number：OM268505

提供者：上海篤瑪生物科技有限公司發(fā)布時(shí)間：2024/8/22 閱讀次數(shù)：26次 >>進(jìn)入該公司展臺(tái)

Product Name	PI3K p85/p55 (phospho Tyr467/199) antibody
Antibody Type	Primary Antibodies
Product description	Rabbit Polyclonal antibody to PI3K P85 (Phospho Tyr467)Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake ａnd glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain ａnd regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. More
Immunogen	Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3K P85.

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	WB
	Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification	Affinity purified

Gene Synonyms	GRB1 p85 p85-ALPHA PIK3R1 phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha phosphatidylinositol 3-kinase regulatory subunit polypeptide 1 (p85 alpha) PI3K regulatory subunit alpha ptdIns-3-kinase regulatory subunit alpha phosphatidyl More
Target	PI3K P85 (Phospho Tyr467)
Molecular Weight(MW)	85 (note)

Application

Western blot analysis of extracts from 293 cells untreated or treated with sorbitol using PI3K P85 (phospho-Tyr467) Antibody .

Application Notes	Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

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