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您的位置:首頁 > 技術(shù)文獻(xiàn) > 產(chǎn)品說明 > Anti-TGF beta1 antibody Catalog Number:OM641708

標(biāo)題Anti-TGF beta1 antibody Catalog Number:OM641708

   

提供者:上海篤瑪生物科技有限公司    發(fā)布時(shí)間:2024/8/21   閱讀次數(shù):15次 >>進(jìn)入該公司展臺(tái)
 

Product Profile

Product Name Anti-TGF beta1 antibody
Antibody Type Primary Antibodies
Immunogen
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIHCWB

 
WB:1:200-1:2000
IHC:1:200-1:1000
Species Reactivity

GoatHumanMouseRat

Concentration 1mg/ml
Purification Protein A

Target Information

Gene Symbol TGFB1
Gene Synonyms
CED
LAP
DPD1
TGFB
IBDIMDE
TGFbeta
TGF-beta1
More 
Gene Full Name transforming growth factor beta 1
Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
More 
Molecular Weight(MW) 44 kDa(Observed:53 kDa)
Cellular Localization Extracellular region or secreted

Application

  • WB

    Western blot analysis using TGF beta1 antibody against Hela (1), A431 (2) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TGF beta1 antibody with DAB staining

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle
Storage Buffer Purified antibody in PBS with 0.05% sodium azide

關(guān)鍵詞:穩(wěn)定性強(qiáng)  特異性強(qiáng)    靈敏度高  

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