標(biāo)題Phospho-NFE2L2-pY576 Antibody Catalog Number：OM217555

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/8/19 閱讀次數(shù)：61次 >>進(jìn)入該公司展臺

Product Name	Phospho-NFE2L2-pY576 Antibody
Antibody Type	Primary Antibodies

Gene Synonyms	NRF2
Alternative Names	NFE2L2 NRF2 Nuclear factor erythroid 2-related factor 2 HEBP1 Nuclear factor erythroid derived 2 like 2 Hide
Molecular Weight(MW)	67827 Da
Function	Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region Hide
Tissue Specificity	Widely expressed. Highest expression in adult muscle, kidney, lung, liver ａnd in fetal muscle
Cellular Localization	Cylasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents

Entrez Gene	4780
Nucleotide Accession	NP_006155

Application

Dot blot analysis of anti-Phospho-NFE2L2-pY576 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Application Notes	DB~~1:500:

Form	Liquid
Storage Instructions	For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.

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