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您的位置:首頁 > 技術(shù)文獻 > 產(chǎn)品說明 > Anti-PGC1 alpha antibody Catalog Number:OM641724

標題Anti-PGC1 alpha antibody Catalog Number:OM641724

   

提供者:上海篤瑪生物科技有限公司    發(fā)布時間:2024/8/16   閱讀次數(shù):23次 >>進入該公司展臺
 

Product Profile

Product Name Anti-PGC1 alpha antibody
Antibody Type Primary Antibodies
Immunogen
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFIHCWB

 
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500
Species Reactivity

HumanMouseRat

Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol PPARGC1A
Gene Synonyms
LEM6
PGC1
PGC1A
PGC-1v
PPARGC1
PGC-1alpha
PGC-1(alpha)
More 
Gene Full Name PPARG coactivator 1 alpha
Gene Summary
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
More 
Molecular Weight(MW) 91 kDa
Source Rabbit
Cellular Localization Cylasm. Nucleus; Nucleus and Nucleus. Nucleus; PML body

Application

  • WB

    Western blot analysis using PGC1 antibody against Hep PC-12 (1) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PGC1 antibody with DAB staining.

  • ICC/IF

    Immunofluorescence analysis of Hela cells using PGC1 alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000
ICC/IF:1:100-1:500

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
 

關(guān)鍵詞:穩(wěn)定性強  特異性強    靈敏度高  

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