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標題Rabbit Anti-Smad3

   

提供者:南京森貝伽生物科技有限公司    發(fā)布時間:2012/7/23   閱讀次數(shù):442次 >>進入該公司展臺

 

Rabbit Anti-Smad3
FROM: Santa Cruz
Catalog Number :HZ98123      
Quantity size :   0.1ml (dilute with pH 7.4    0.01 M PBS or antibody diluent )
 
Background:  Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP-2 and BMP-4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
 
pecificity :   
        Anti-Smad3 is a rabbit monoclonal antibody unconjugated                
         specific for Smad3 of human, mouse, rat          
         use for western blotting,elisa,immunoprecipitation and immunohistochemistry
         Protein G affinity chromatography purification, purity :>95%
         Isotype:  IgG
         mol wt:  54kDa
 
Rabbit Anti-Smad3
Application :  
        Western blotting 1:100-500                
         Immunohistochemistry 1:100-500                 
         ELISA 1:500-1000                   
         Optimal working dilutions must be determined by the end user.
 
Storage: Store at -20 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Rabbit Anti-Smad3

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