96孔板分析

色素上皮衍生因子（PEDF）是一種多能神經(jīng)營(yíng)養(yǎng)因子，在中樞神經(jīng)系統(tǒng)和視網(wǎng)膜中均具有很強(qiáng)的活性。到目前為止，PEDF是在哺乳動(dòng)物的眼腔中所發(fā)現(xiàn)的最強(qiáng)的抗血管生長(zhǎng)因子。有趣的是，最近的研究顯示眼部PEDF水平的降低與糖尿病視網(wǎng)膜病變和其他神經(jīng)視網(wǎng)膜營(yíng)養(yǎng)不良性疾病存在相關(guān)性。并且，PEDF表現(xiàn)出來(lái)的神經(jīng)營(yíng)養(yǎng)特性和抗血管生成的特性，提示這種蛋白在控制與腫瘤生長(zhǎng)相關(guān)的新血管生成中具有潛在的治療價(jià)值。為了便于研究這一重要的絲氨酸蛋白酶抑制蛋白超家族的成員-PEDF，我們研發(fā)了一種敏感的PEDF ELISA試劑盒，這種試劑盒通過使用多克隆抗體特異性的檢測(cè)存在于人的玻璃體和其他組織中的天然PEDF蛋白。與其他的商業(yè)性的PEDF ELISA試劑盒相比較，我們的PEDF ELISA試劑盒的敏感性幾乎是其他同類產(chǎn)品的50倍。事實(shí)上，我們的研究起初即以接近于其他PEDF ELISA試劑盒產(chǎn)品檢測(cè)限的PEDF濃度進(jìn)行實(shí)驗(yàn)的。如果您的研究需要對(duì)PEDF進(jìn)行定量，我們的PEDF ELISA試劑盒將會(huì)是您的最佳選擇對(duì)象。

主要特點(diǎn)：

檢測(cè)限....范圍…..敏感性是同類產(chǎn)品的50倍

保存和操作：

保存在4 ºC，不要冷凍保存。產(chǎn)品自發(fā)貨日期起至少可以穩(wěn)定保存6個(gè)月。

PEDF ELISA Kits

96-Well Microplate Assay

Pigment epithelium-derived factor (PEDF) is a multipotent neurotrophic factor with potent activity both in the central nervous system ａnd in the retina. To date, PEDF is the most potent angiogenic inhibitor found in the mammalian ocular compartment. Interestingly, recent studies have shown that decreased ocular levels of PEDF are associated with diabetic retinopathy ａnd other neuroretinal dystrophic diseases. In addition, the neurotropic ａnd anti-angiogenic properties of PEDF suggest this protein is of potential therapeutic value for control of neovascularization associated with tumor growth.   To facilitate research on this important member of the serpin protein superfamily, we have developed a sensitive PEDF ELISA using polyclonal antibodies that specifically detects native PEDF protein in human vitreous ａnd other tissues.   Compared to other commercially-available PEDF ELISA kits, our PEDF ELISA is nearly 50-times more sensitive than the competitor＇s product. In fact, our assay starts at PEDF concentrations that are near the limit-of-detection for other PEDF ELISAs (see above).  If you need to quantify PEDF levels in your studies, our PEDF ELISA kit is the best solution to consider!

KIT FEATURES:

Limits of detection... range... 50X better than competitors＇ assay.

STORAGE & HANDLING:  

Store at 4ºC.  DO NOT FREEZE. Product is stable for at least six months from date of shipment.