Interleukin-2 (IL-2, IL2) 僅由活化的 T 細胞產(chǎn)生。IL-2 促進抗原激活的 T 細胞和 NK 細胞的增殖、分化和存活。

艾美捷抗人IL-2單抗MT8G10：

這種單克隆抗體能夠在 ELISA 和 ELISpot 等免疫分析中靈敏且特異地檢測人 IL-2。該抗體還適用于使用流式細胞術(shù)檢測 IL-2。

推薦 MT8G10 作為 ELISA 和 ELISpot 中的檢測抗體與捕獲抗體 MT2A91/2C95 結(jié)合使用。

MT8G10 也可與 FITC 偶聯(lián)。

艾美捷抗人IL-2單抗MT8G10物種交叉反應(yīng)：

單克隆抗體與來自非人類靈長類動物的 IL-2 發(fā)生交叉反應(yīng)。

僅供研究使用 (RUO)。不用于診斷過程。

艾美捷抗人IL-2單抗MT8G10文獻參考：

Douthwaite, J., et al. (2016). A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, ａnd FcRn Binding. The Journal of Immunology.

Forghieri, F., et al. (2016). Chronic ａnd recurrent benign lymphadenopathy without constitutional symptoms associated with human herpesvirus-6B reactivation. British Journal of Haematology.

Korber, N., et al. (2016). Validation of an IFNgamma/IL2 FluoroSpot assay for clinical trial monitoring. J Transl Med.

Mazor, R., et al. (2017). Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epies in PE38. Cellular immunology.

Starc, N., et al. (2017). Phenotypic ａnd functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome. Cytotherapy.

相關(guān)研究：

3445-1HP-2 ELISA Pro：人 IL-2 2 板

3445-7 抗人 IL-2 mAb (MT8G10)，FITC 100 測試

3445M-1HP-2 ELISA Pro：猴子 IL-2 2 板

來源：https://www.amyjet.com/products/3445-6-1000.shtml