白細(xì)胞介素 8（IL-8，IL8，也稱為 CXCL8）是一種由不同類型的細(xì)胞產(chǎn)生的促炎細(xì)胞因子，包括單核細(xì)胞、巨噬細(xì)胞和內(nèi)皮細(xì)胞。炎癥刺激，如 LPS，強(qiáng)烈誘導(dǎo)單核細(xì)胞產(chǎn)生 IL-8。

艾美捷抗人IL-8 (CXCL8)單抗MT8F19：

這種單克隆抗體能夠在 ELISA 中靈敏和特異地檢測人 IL-8。

艾美捷推薦 MT8F19 作為 ELISA 中的檢測抗體與捕獲抗體 MT8H6 結(jié)合使用。

艾美捷抗人IL-8 (CXCL8)單抗MT8F19配套研究：

3310-8-1000 ELISA 偶聯(lián)物：鏈霉親和素-ALP 1 ml

3310-9-1000 ELISA/ELISpot 偶聯(lián)物：Streptavidin-HRP 1 ml

3560-1-250 抗人 IL-8 (CXCL8) mAb (MT8H6/8F19)，未偶聯(lián) 250 µg

艾美捷抗人IL-8 (CXCL8)單抗MT8F19參考文獻(xiàn)：

Arruda-Silva, F., et al. (2017). Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists ａnd TNFalpha. Frontiers in cellular ａnd infection microbiology.

Castellucci, M., et al. (2015). IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 ａnd TNF-alpha expression in monocytes: Implications for chronic obstructive pulmonary disease. The Journal of allergy ａnd clinical immunology.

Panda, S. K., et al. (2018). Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models. The Journal of clinical investigation.

Skrlec, K., et al. (2017). Evasin-displaying lactic acid bacteria bind different chemokines ａnd neutralize CXCL8 production in Caco-2 cells. Microb Biotechnol.

Tamassia, N., et al. (2018). A Reappraisal on the Potential Ability of Human Neutrophils to Express ａnd Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It. Front Immunol.

來源：https://www.amyjet.com/products/3560-6-1000.shtml