FGF21 是什么？

成纖維細(xì)胞生長因子21( fibroblast growth factor 21，FGF21) 屬于成纖維細(xì)胞生長因子家族FGF19( fibroblast growth factor 19，FGF19) 的亞型，不具有促成纖維細(xì)胞生長活性，且不與肝素特異性結(jié)合，是種調(diào)節(jié)機(jī)體代謝的分泌型蛋白。在骨骼肌、腎臟、心臟以及血管和脂肪組織中 fgf21 表達(dá)比肝臟中高約 7～10 倍。FGF21可靶向腦、心臟、骨骼肌以及腎臟和腸等多種組織器官發(fā)揮作用。

BioVendor 艾美捷 FGF21檢測試劑盒針對成纖維細(xì)胞生長因子21的研究有著比較深刻和有意義的影響。

BioVendor 艾美捷FGF21（人）檢測試劑盒標(biāo)曲：

BioVendor 艾美捷 FGF21檢測試劑盒已發(fā)表文章（部分）：

Ahola S, Auranen M, Isohanni P, Niemisalo S, Urho N, Buzkova J, Velagapudi V, Lundbom N, Hakkarainen A, Muurinen T, Piiril? P, Pietil?inen KH, Suomalainen A.Modified Atkins diet induces subacute selective ragged-red-fiber lysis inmitochondrial myopathy patients. EMBO Mol Med. 2016 Nov 2;8(11):1234-1247.

Bisgaard A, S?rensen K, Johannsen TH, Helge JW, Andersson AM, Juul A.Significant gender difference in serum levels of fibroblast growth factor 21 inDanish children ａnd adolescents. Int J Pediatr Endocrinol. 2014;2014(1):7.

BonDurant LD, Ameka M, Naber MC, Markan KR, Idiga SO, Acevedo MR, Walsh SA,Ornitz DM, Potthoff MJ. FGF21 Regulates Metabolism Through Adipose-Dependent ａnd -Independent Mechanisms. Cell Metab. 2017 Apr 4;25(4):935-944.e4.

Bookout AL, de Groot MH, Owen BM, Lee S, Gautron L, Lawrence HL, Ding X,Elmquist JK, Takahashi JS, Mangelsdorf DJ, Kliewer SA. FGF21 regulates metabolismand circadian behavior by acting on the nervous system. Nat Med. 2013Sep;19(9):1147-52.