CalBioreagents/艾美捷  ID蛋白單克隆抗體（cat#：M082）

蛋白質(zhì)家族，Id1，Id2，Id3和Id4。這些蛋白質(zhì)初是作為蛋白質(zhì)被發(fā)現(xiàn)的參與細(xì)胞的陰性控制區(qū)別Id蛋白起著陰性作用通過(guò)物理機(jī)制調(diào)節(jié)轉(zhuǎn)錄與組轉(zhuǎn)錄因子的相互作用被稱(chēng)為bHLH（堿性螺旋-環(huán)-螺旋）蛋白質(zhì)。Id蛋白與bHLH蛋白在細(xì)胞內(nèi)相互作用阻止DNA與HLH結(jié)合的方式蛋白質(zhì)。由于這項(xiàng)活動(dòng)蛋白質(zhì)被命名為Id（DNA抑制劑）綁定）。Id蛋白也被發(fā)現(xiàn)與與其他些蛋白質(zhì)如Rb，Ets，Paz、MIDA-1和SREBP-1c。Id蛋白可能在協(xié)調(diào)基因方面發(fā)揮中心作用表達(dá)、細(xì)胞增殖、腫瘤發(fā)生和血管生成。

Id蛋白被發(fā)現(xiàn)是在許多類(lèi)型中過(guò)度表達(dá)，包括膠質(zhì)母細(xì)胞瘤髓母細(xì)胞瘤神經(jīng)母細(xì)胞瘤，胰腺癌、甲狀腺癌、鱗狀細(xì)胞癌細(xì)胞癌，乳腺癌，子宮內(nèi)膜癌癌癥、宮頸癌、黑色素瘤和網(wǎng)膜母細(xì)胞瘤。越來(lái)越多的人證據(jù)表明Id1和Id3在血管生成。Id1-/-，Id3中的實(shí)驗(yàn)-/-敲除小鼠表明，隨著Id的丟失表達(dá)：無(wú)血管生成，無(wú)血管生成腫瘤的后續(xù)生長(zhǎng)。

CalBioreagents/艾美捷  ID蛋白單克隆抗體相關(guān)研究：

ANALYTE     TYPE   DESCRIPTION   APPLICATION   PART #  PKG

Id1 Rabbit Monoclonal Anti-Mouse Id1 Clone 37-2 WB, IHC M082  50 ug

Id1 Rabbit Monoclonal Anti-Mouse Id1 Clone 37-2 WB, IHC M083 100 ug

Id1 Rabbit Monoclonal Anti-Mouse Id1 Clone 37-2 WB, IHC M084 1 mg

Id1 Rabbit Monoclonal Anti-Human/Mouse Id1 Clone 195-14 WB, IHC M085 50 ug

Id1 Rabbit Monoclonal Anti-Human/Mouse Id1 Clone 195-14 WB, IHC M086 100 ug

Id1 Rabbit Monoclonal Anti-Human/Mouse Id1 Clone 195-14 WB, IHC M087 1 mg

Id1 Rabbit Monoclonal Anti-Human Id1 Clone 5-3 WB M088 50 ug

Id1 Rabbit Monoclonal Anti-Human Id1 Clone 5-3 WB M089 100 ug

Id1 Rabbit Monoclonal Anti-Human Id1 Clone 5-3 WB M090 1 mg

Id2 Rabbit Monoclonal Anti Human/Mouse Id2 Clone 9-2-8 WB, IHC M213 50 ug

Id2 Rabbit Monoclonal Anti Human/Mouse Id2 Clone 9-2-8 WB, IHC M214 100 ug

Id2 Rabbit Monoclonal Anti Human/Mouse Id2 Clone 9-2-8 WB, IHC M215   1 mg

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 6-1 WB M094   50 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 6-1 WB M095 100 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 6-1 WB M096 1 mg

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 16-1 WB M097 50 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 16-1 WB M098    100 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 16-1 WB M099 1 mg

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 17-3 WB, IHC (IHC for Human only) M100 50 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 17-3 WB, IHC (IHC for Human only) M101 100 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 17-3 WB, IHC (IHC for Human only) M102 1 mg

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 42-1 WB M103 50 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 42-1 WB M104 100 ug

Id3 Rabbit Monoclonal Anti-Human/Mouse Id3 Clone 42-1 WB M105 1 mg

Id4 Rabbit Monoclonal Anti-Human/Mouse Id4 Clone 82-12 WB, IHC M106 50 ug

Id4 Rabbit Monoclonal Anti-Human/Mouse Id4 Clone 82-12 WB, IHC M107 100 mg

Id4 Rabbit Monoclonal Anti-Human/Mouse Id4 Clone 82-12 WB, IHC M108 1 mg

艾美捷科技是CalBioreagents的中國(guó)代理商，為科研工作者提供優(yōu)質(zhì)的產(chǎn)品與服務(wù)。