產(chǎn)品展示
優(yōu)質(zhì)供應
詳細內(nèi)容
【英語名稱】:Caspase-8 Polyclonal Antibody
【產(chǎn)品類型】:一抗
【供應商】:Abbkine
【產(chǎn)品貨號】:ABP50858
【產(chǎn)品規(guī)格】:30ul/100ul/200ul
【背景資料】:CASP8 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.
蛋白別名為:CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH;基因ID為:841;蛋白質(zhì)ID:Q14790
【應用類型】:WB,IHC-p,ELISA
補充:*優(yōu)的抗體稀釋比例需要基于客戶實驗進行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
【免疫原】:合成多肽:human Caspase-8 around the non-phosphorylation site of S347.
【來源宿主】:兔
【反應性】:人,小鼠,大鼠
【保存建議】:廠家推薦藍冰運輸.在發(fā)貨后能在-20℃保存1年.為限度的避免損失,請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.
本產(chǎn)品為液體形式,溶解于PBS緩沖液中,含50%甘油,0.5%BSA和0.02%疊氮化鈉.
【產(chǎn)品說明】:點擊:Caspase-8 多克隆抗體查看更詳細產(chǎn)品說明,更多應用、儲存、價格、貨期等信息請致電垂詢Abbkine中國區(qū)域授權(quán)總代理艾美捷科技有限公司。更多特色試劑盒、特色抗體以及特色試劑等產(chǎn)品評論,請點擊查看每日生物評論網(wǎng)站。
Abbkine致力于為全球生命科學研究和醫(yī)療發(fā)展提供*新的產(chǎn)品和技術。Abbkine設計、開發(fā)、生產(chǎn)并銷售了一系列獨特的產(chǎn)品,包括生命科學領域研究相關的抗體、研究試劑以及細胞功能分析產(chǎn)品。Abbkine的產(chǎn)品為科學研究中的挑戰(zhàn)提供卓有成效的解決方案,從而為全球的科學家節(jié)省時間并提高研究效率。作為Abbkine的中國區(qū)域總代理,艾美捷科技有限公司憑借豐富的專業(yè)經(jīng)驗,將一如既往的為中國區(qū)域客戶提供Abbkine優(yōu)質(zhì)的產(chǎn)品和技術服務。
艾美捷科技有限公司品線覆蓋生物研究各個領域,主要包括:分子生物學(核酸蛋白研究工具、cDNA/RNA、轉(zhuǎn)染試劑、植物組培/細胞培養(yǎng)、生化試劑及試劑盒),試劑(蛋白酶抑制劑、化合物、熒光染料/探針、動物血清)、抗體(一抗、二抗、封閉血清), 蛋白及試劑盒(細胞因子/重組蛋白、細胞凋亡/代謝/損傷、表觀遺傳、天然免疫)等。艾美捷為您尋找并提供*優(yōu)的產(chǎn)品解決方案、*完備的物流服務、*及時的售后服務。如果您對上述產(chǎn)品線感興趣,請致電免費服務熱線到艾美捷垂詢相關產(chǎn)品信息及完整實驗解決方案。
產(chǎn)品標簽:Caspase-8,Caspase-8ABP50858,Caspase-7 Polyclonal Antibody,Caspase-8 多克隆抗體,Caspase-8 Polyclonal Antibody