產(chǎn)品展示

Recombinant Murine IL-10 Peprotech 優(yōu)勢產(chǎn)品

點擊次數(shù)：44發(fā)布時間：2016/1/26 14:07:46

更新日期：2016/1/26 14:07:46

所在地：中國大陸

產(chǎn)品型號：210-10

簡單介紹：生長因子此類產(chǎn)品包括人、小鼠或大鼠的細胞外蛋白，多數(shù)情況下可啟始或影響通過細胞表面受體傳遞的信號。下列產(chǎn)品包括人、小鼠和大鼠的白細胞介素、集落刺激因子、生長因子、干擾素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受體、細胞外結合蛋白、非抑制型絲氨酸蛋白酶抑制劑及其他免疫調(diào)節(jié)蛋白等。

相關標簽：Recombinant Murine IL-10 Peprotech 優(yōu)勢產(chǎn)品

優(yōu)質(zhì)供應

詳細內(nèi)容

Recombinant Murine IL-10 Peprotech 優(yōu)勢產(chǎn)品

產(chǎn)品編號:

210-10

別名:

B-TCGF, CSIF, TGIF

描述:

IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells ａnd keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 ａnd TNF-α. Like IL-4, IL-10 enhances humoral immune responses ａnd attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.

氨基酸序列:

MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S

來源:

E.coli

純度:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

生物活性:

PeproTech＇s Murine IL-10 is fully biologically active as measured by the dose-dependent co-stimulation (with IL-4) of the proliferation of murine MC/9 cells. The ED₅₀ was found to be < 2 ng/ml, corresponding to a specific activity of > 5 x 10⁵ units/mg.

交叉反應:

Human, Mouse, Rat

研究領域: