產(chǎn)品展示
Recombinant Human IL-1β Peprotech進口原裝
點擊次數(shù)：29發(fā)布時間：2016/1/26 13:30:31
更新日期：2016/1/26 13:30:31
所 在 地：中國大陸
產(chǎn)品型號：200-01B
優(yōu)質(zhì)供應(yīng)
詳細內(nèi)容
產(chǎn)品編號:
200-01B
別名:
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, ａnd other epithelial cells. Both IL-1α ａnd IL-1β bind to the same receptor ａnd have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity, ａnd the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.
氨基酸序列:
APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine D10S cells is ≤ 1.0 pg/ml, corresponding to a specific activity of ≥ 1 x 109 units/mg.
交叉反應(yīng):
Frog, Monkey, Mouse, Rabbit, Rat, Sheep, Human, Mouse + Chicken, Cow, Human + Rat, Pig
研究領(lǐng)域:
原產(chǎn)國:
USA
僅用于研究。不適用于診斷或治療。
