產(chǎn)品展示
Recombinant Murine IFN-r Peprotech現(xiàn)貨
點擊次數(shù)：31發(fā)布時間：2016/1/26 9:19:29
更新日期：2016/1/26 9:19:29
所 在 地：中國大陸
產(chǎn)品型號：315-05
優(yōu)質(zhì)供應(yīng)
詳細內(nèi)容
產(chǎn)品編號:
315-05
別名:
Immune Interferon, type II interferon, T cell interferon, MAF
描述:
IFN-γ is an acid-labile interferon produced by CD4 ａnd CD8 T lymphocytes, as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting, cells ａnd antigen-recognizing B ａnd T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial ａnd anti-tumor responses of macrophages, NK cells, ａnd neutrophils. Human IFN-γ is species-specific ａnd is biologically active only in human ａnd primate cells. Recombinant Murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.
氨基酸序列:
MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
交叉反應(yīng):
Rabbit, Rat, Mouse, Mouse + Chicken, Human, Cow, N/A, Mouse + Parasite
研究領(lǐng)域:
原產(chǎn)國:
USA
僅用于研究。不適用于診斷或治療。
