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Recombinant Human GM-CSF Peprotech進(jìn)口原裝

點(diǎn)擊次數(shù)：32發(fā)布時(shí)間：2016/1/26 9:11:45

更新日期：2016/1/26 9:11:45

所在地：中國大陸

產(chǎn)品型號(hào)：300-03

簡單介紹：生長因子此類產(chǎn)品包括人、小鼠或大鼠的細(xì)胞外蛋白，多數(shù)情況下可啟始或影響通過細(xì)胞表面受體傳遞的信號(hào)。下列產(chǎn)品包括人、小鼠和大鼠的白細(xì)胞介素、集落刺激因子、生長因子、干擾素、脂肪因子、BMP蛋白、FGFs、TNFs、可溶性受體、細(xì)胞外結(jié)合蛋白、非抑制型絲氨酸蛋白酶抑制劑及其他免疫調(diào)節(jié)蛋白等。

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詳細(xì)內(nèi)容

Recombinant Human GM-CSF Peprotech進(jìn)口原裝

產(chǎn)品編號(hào):

300-03

別名:

Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α

描述:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils ａnd macrophages, ａnd promotes the proliferation ａnd development of early erythroid megakaryocytic ａnd eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts ａnd T-lymphocytes. GM-CSF inhibits neutrophil migration ａnd enhances the functional activity of the mature end-cells. The human ａnd murine molecules are species-specific ａnd exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids, containing two intramolecular disulfide bonds ａnd two potential N-linked glycosylation sites.

氨基酸序列:

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

來源:

E.coli

純度:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

交叉反應(yīng):

Human, Bacteria, Mouse, Leech, Pig, Human + Mouse

研究領(lǐng)域: