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技術(shù)文章

Anti-RAB21 antibody Catalog Number:OM642604

點(diǎn)擊次數(shù):41 發(fā)布時(shí)間:2024/10/8 15:24:41
 

Product Profile

Product Name Anti-RAB21 antibody
Antibody Type Primary Antibodies
Immunogen
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFIHC

 
IHC:1:200-1:2000
ICC/IF:1:100-1:500
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Protein A

Target Information

Gene Symbol RAB21
Gene Synonyms
KIAA0118
Gene Full Name RAB21, member RAS oncogene family
Gene Summary
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]
More 
Molecular Weight(MW) 24KD
Cellular Localization Cell projection, Cylasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane

Application

  • IHC

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using RAB21 antibody with DAB staining.

  • IHC

    Immunohistochemical analysis of paraffin-embedded renal carcinoma tissues using RAB21 antibody with DAB staining.

  • ICC/IF

    Immunofluorescence analysis of A549 cells using RAB21 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes
IHC:1:200-1:2000
ICC/IF:1:100-1:500

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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