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技術(shù)文章

LIMS1 antibody Catalog Number：OM261584

點(diǎn)擊次數(shù)：32 發(fā)布時間：2024/9/29 14:29:34
 

Product Profile

Product Name LIMS1 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to Pinch 1 (LIM ａnd senescent cell antigen-like domains 1)The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq]
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Immunogen 
Recombinant protein encompassing a sequence within the center region of human LIMS1. The exact sequence is proprietary.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWB
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

Human
Predicted Reactivity Mouse, Rat, Zebrafish, Xenopus laevis, Pig, Chicken, BovineMouse (99%), Rat (99%), Zebrafish (95%), Xenopus laevis (97%), Pig (98%), Chicken (95%), Bovine (99%)
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
PINCH antibody
PINCH1 antibody
LIMS1 antibody
renal carcinoma antigen NY-REN-48 antibody
particularly interesting new Cys-His protein 1 antibody
LIM ａnd senescent cell antigen-like-containing domain protein 1 antibody
LIM ａnd senescent cell antigen-l
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Molecular Weight(MW) 37 kDa (note) (7)

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded BT474 xenograft, using Pinch 1 antibody at 1:100 dilution.

  • Application

    Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE diluted at 1:1000

Positive Control A549 , HeLa , HCT116
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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