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技術(shù)文章

MCM7 antibody Catalog Number：OM262670

點擊次數(shù)：37 發(fā)布時間：2024/9/27 15:00:59
 

Product Profile

Product Name MCM7 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to MCM7The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) ａnd may be involved in the formation of replication forks ａnd in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein ａnd MCM2, 4 ａnd 6 proteins possesses DNA helicase activity, ａnd may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, ａnd may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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Immunogen 
Recombinant protein of human MCM7

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ICC/IFIHC-PWB
 
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
minichromosome maintenance complex component 7
P1.1-MCM3
P1CDC47
PNAS146
P85MCM
CDC47
MCM2
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Target MCM7
Molecular Weight(MW) 81 kDa (note)

Application

  • Application

    WB analysis of extracts from various cells using MCM7 antibody.

  • Application

    IHC-P analysis of human breast cancer using MCM7 antibody at a dilution of 1:200.

  • Application

    IHC-P analysis of human esophageal cancer using MCM7 antibody at a dilution of 1:200.

  • Application

    IHC-P analysis of human rectal cancer using MCM7 antibody at a dilution of 1:200.

  • Application

    IHC-P analysis of rat brain using MCM7 antibody at a dilution of 1:200.

  • Application

    ICC/IF analysis of HeLa cells using MCM7 antibody (green) ａnd DAPI (blue).

Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:

Additional Information

Form Liquid
Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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