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技術(shù)文章

MCM2 antibody Catalog Number：OM262643

點(diǎn)擊次數(shù)：35 發(fā)布時(shí)間：2024/9/27 14:48:48
 

Product Profile

Product Name MCM2 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to MCM2The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) ａnd may be involved in the formation of replication forks ａnd in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, ａnd 7, ａnd has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, ａnd thus regulated by, protein kinases CDC2 ａnd CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
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Immunogen 
Recombinant protein of human MCM2

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHCIHC-PWB
 
WB 1:500 - 1:2000, IHC 1:50 - 1:200:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
BM28
MITOTIN
D3S3194
minichromosome maintenance complex component 2
CCNL1
cdc19
CDCL1
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Target MCM2
Molecular Weight(MW) 102 kDa (note)

Application

  • Application

    Western blot analysis of extracts of various cell lines, using MCM2 antibody.

  • Application

    Immunohistochemistry of paraffin-embedded human normal colon using MCM2 antibody at dilution of 1:200 (400x lens).

Application Notes
WB 1:500 - 1:2000, IHC 1:50 - 1:200:

Additional Information

Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 

原創(chuàng)作者：上海篤瑪生物科技有限公司

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