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技術(shù)文章

MCM2 Antibody Catalog Number：OM284351

點(diǎn)擊次數(shù)：30 發(fā)布時(shí)間：2024/9/27 14:30:09
 

Product Profile

Product Name MCM2 Antibody
Antibody Type Primary Antibodies
Product description 
MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) ａnd may be involved in the formation of replication forks ａnd in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, ａnd 7, ａnd has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, ａnd thus regulated by protein kinases CDC2 ａnd CDC7. Double serines at positions 26 ａnd 27 are conserved in rat ａnd mouse. High homology >88% to similar proteins from several other species. Expected broad reactivity to various lysates.
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Immunogen 
MCM2 antibody was raised against amino acids 21 - 31 of MCM2 (Human).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIFIHCWB
 
MCM2 antibody can be used in Western Blot, ａnd immunohistochemistry starting at 10 μg/mL.:
Species Reactivity

HumanMouseRatYeast
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol MCM2
Alternative Names
MCM2
BM28
Cell devision cycle-like 1
D3S3194
Cdc19
Cyclin-like 1
KIAA0030
Nuclear protein BM28
CDCL1
MITOTIN
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Database Links

Entrez Gene 4171
Protein Accession P49736

Application

  • Application

    Immunohistochemistry staining of MCM2 in skin tissue using MCM2 Antibody.

Application Notes
MCM2 antibody can be used in Western Blot, ａnd immunohistochemistry starting at 10 μg/mL.:

Additional Information

Form Liquid
Storage Instructions Aliquot ａnd store MCM2 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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