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技術文章

Rabbit anti-PHB polyclonal antibody - C-terminal region Catalog Number:OM106032

點擊次數(shù):23 發(fā)布時間:2024/9/26 13:58:12
 

Product Profile

Product Name Rabbit anti-PHB polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen
The immunogen for anti-PHB antibody: synthetic peptide directed towards the C terminal of human PHB

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHC

 
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHumanMouseRatZebra Fish

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol PHB
Gene Synonyms
PHB1
Gene Full Name Prohibitin
Gene Summary
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
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Alternative Names
PHB1
Molecular Weight(MW) 30kDa
Sequence 272 amino acids

Database Links

Entrez Gene 5245
SwissProt ID P35232
Protein Accession NP_002625

Application

  • Immunohistochemical

     

  • Western blot

    0.2-1 ug/ml
    Positive Control: Jurkat cell lysate

Application Notes
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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