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技術(shù)文章

FOXP2 Antibody Catalog Number：OM279142

點(diǎn)擊次數(shù)：25 發(fā)布時(shí)間：2024/9/26 13:44:37
 

Product Profile

Product Name FOXP2 Antibody
Antibody Type Primary Antibodies
Product description 
FOXP2 is an evolutionarily conserved transcription factor expressed in fetal ａnd adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, ａnd contains a FOX DNA-binding domain ａnd a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech ａnd language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene ａnd another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.1) Sanjuan, J., et al., (2006) Psychiatr. Genet. 16 (2), 67-72.
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Immunogen 
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXP2.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAWB
 
FOXP2 antibody can be used for detection of FOXP2 by ELISA at 1:62500. FOXP2 antibody can be used for detection of FOXP2 by western blot at 0.5 μg/mL, ａnd HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

DogHumanRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol FOXP2
Alternative Names
FOXP2
SPCH1
CAGH44
TNRC10
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Molecular Weight(MW) 80 kDa, 83 kDa

Database Links

Entrez Gene 93986
Protein Accession NP_055306

Application

  • Application

    Antibody used in WB on Human HepG2 at 0.5 ug/ml.

  • Application

    Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

  • Application

    Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.

Positive Control 1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes
FOXP2 antibody can be used for detection of FOXP2 by ELISA at 1:62500. FOXP2 antibody can be used for detection of FOXP2 by western blot at 0.5 μg/mL, ａnd HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store FOXP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
 

原創(chuàng)作者：上海篤瑪生物科技有限公司

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