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技術(shù)文章

Rabbit anti-G6PD polyclonal antibody - middle region Catalog Number:OM117661

點(diǎn)擊次數(shù):78 發(fā)布時間:2024/9/25 15:17:45
 

Product Profile

Product Name Rabbit anti-G6PD polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen
The immunogen for anti-G6PD antibody: synthetic peptide directed towards the middle region of human G6PD

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

 
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogGuinea PigHorseHumanMouseRabbitRatSheep

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol G6PD
Gene Synonyms
G6PD1
Gene Full Name Glucose-6-phosphate dehydrogenase
Gene Summary
G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
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Alternative Names
G6PD1
Molecular Weight(MW) 57kDa
Sequence 515 amino acids

Database Links

Entrez Gene 2539
SwissProt ID P11413
Protein Accession NP_000393

Application

  • Western blot

    Host: Rabbit
    Target Name: NSUN6
    Sample Tissue: Human Fetal Lung
    Antibody Dilution: 1.0ug/ml

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:62500
    Positive Control: MCF7 cell lysate

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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