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技術(shù)文章

Myelin basic protein antibody Catalog Number：OM264380

點(diǎn)擊次數(shù)：36 發(fā)布時(shí)間：2024/9/25 15:14:35
 

Product Profile

Product Name Myelin basic protein antibody
Antibody Type Primary Antibodies
Product description 
Mouse monoclonal antibody [22] to Myelin basic proteinThe protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes ａnd Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow ａnd the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli ａnd the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts ａnd gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons ａnd produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit ａnd that this arra
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Immunogen 
Human myelin basic protein

Key Feature

Clonality Monoclonal
Isotype IgG2
Clone Number 22
Host Species Mouse
Tested Applications

IHCIHC-FIHC-P
 
IHC:1:50~1:200
IHC-F:1:50~1:100
IHC-P:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity

Human
Concentration 1 mg/ml

Target Information

Gene Synonyms
MBP
myelin basic protein
Target Myelin basic protein
Tissue Specificity This antibody recognizes an epie of myelin basic protein between amino acids 84-89.

Application

  • Application

    IHC analysis of white matter in human brain tissue using Myelin basic protein antibody [22].

Application Notes
IHC:1:50~1:200
IHC-F:1:50~1:100
IHC-P:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
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Additional Information

Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing ａnd thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Tissue Culture Supernatant with 0.09%Sodium Azide

原創(chuàng)作者：上海篤瑪生物科技有限公司

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