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Myelin basic protein antibody Catalog Number：OM264370

點(diǎn)擊次數(shù)：37 發(fā)布時(shí)間：2024/9/25 15:06:05
 

Product Profile

Product Name Myelin basic protein antibody
Antibody Type Primary Antibodies
Product description 
Rabbit polyclonal to Myelin Basic Protein - Oligodendrocyte MarkerThe classic group of Myelin basic protein (MBP) isoforms (isoforms 4-14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation ａnd stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoforms 1-3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, ａnd may also be involved in signaling pathways in T-cells ａnd neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
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Immunogen 
Human myelin basic protein isolated from normal human brain.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCIHC-P
 
For IHC-P: Use at a dilution of 1:50-1:100 in an ABC method. We suggest an incubation period of 30 minutes at RT. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
4155
Myelin basic protein
MBP
MGC99675
P02686
159430
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Target Myelin basic protein
Tissue Specificity This antibody reacts with human myelin basic protein ａnd oligodendrocytes of white matter in brain ａnd spinal cord. Grey matter stains weakly. This antibody also stains peripheral nerves.
Cellular Localization Cylasmic side of myelin

Application

  • Application

    Formalin fixed paraffin embedded human brain stained with MBP antibody .

  • Application

    at a dilution of 1/1000, staining Myelin Basic Protein (MBP; Alexa 488 secondary at 1/2000) in the cortex of rat brain tissue (30m thick coronal sections). Staining was obtained following free floating IHC (see protocol link for detailed descript

  • Application

    at a dilution of 1/1000, staining Myelin Basic Protein (MBP; Alexa 488 secondary at 1/2000) in the cortex ａnd hippocampus of rat brain tissue (30m thick coronal sections). Staining was obtained following free floating IHC (see protocol link for d

  • Application

    Detection of Myelin basic protein by IHC in Human Breast

Positive Control Brain
Application Notes
For IHC-P: Use at a dilution of 1:50-1:100 in an ABC method. We suggest an incubation period of 30 minutes at RT. Optimal dilutions/concentrations should be determined by the researcher.:

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution, aliquot ａnd store at 4°C.
Storage Buffer Contains sodium azide

原創(chuàng)作者：上海篤瑪生物科技有限公司

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