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Myelin Basic Protein Antibody, Monoclonal Catalog Number：OM285643

點擊次數(shù)：40 發(fā)布時間：2024/9/25 14:59:04
 

Product Profile

Product Name Myelin Basic Protein Antibody, Monoclonal
Antibody Type Primary Antibodies
Product description 
Suitable for use in ELISA, Western Blot, Immunohistochemistry ａnd quantification of myelin basic protein. Other applications have not been tested. Recognizes residues 130-136 in human myelin basic protein (21.5kD ａnd 18.5kD molecular forms). Species Crossreactivity: Primate, rabbit, sheep, goat, rat ａnd mouse. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation ａnd stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) found in bone marrow ａnd the immune system may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, ａnd may also be involved in signaling pathways in T-cells ａnd neural cells.
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Immunogen 
Myelin Basic Protein monoclonal antibody was raised against amino acids 130 - 136 of Myelin Basic Protein (Human).

Key Feature

Clonality Monoclonal
Isotype IgG2b
Host Species Mouse
Tested Applications

ELISAIHCWB
 
Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 10 μg/mL, ａnd flow cytometry.:
Species Reactivity

GoatHumanMousePrimateRabbitRatSheep
Concentration 1 mg/ml
Purification Protein G

Target Information

Gene Symbol MBP
Alternative Names
MBP
Myelin A1 protein
Myelin basic protein

Database Links

Entrez Gene 4155
Protein Accession P02686

Application

  • Application

    Immunohistochemistry staining of Myelin Basic Protein in brain, oligodendrocytes tissue using Myelin Basic Protein Monoclonal Antibody.

Application Notes
Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 10 μg/mL, ａnd flow cytometry.:

Additional Information

Form Liquid
Storage Instructions Myelin Basic Protein antibody should be stored at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer PBS, pH 7.4, contains no preservative.
 

原創(chuàng)作者：上海篤瑪生物科技有限公司

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