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技術(shù)文章

NQO1 antibody Catalog Number：OM265887

點擊次數(shù)：141 發(fā)布時間：2024/9/24 15:08:07
 

Product Profile

Product Name NQO1 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, qui 1)This gene is a member of the NAD(P)H dehydrogenase (qui) family ａnd encodes a cylasmic 2-electron reductase. This FAD-binding protein forms homodimers ａnd reduces quis to hydroquis. This protein＇s enzymatic activity prevents the one electron reduction of quis that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, ａnd susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors ａnd is also associated with Alzheimer＇s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
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Immunogen 
Recombinant protein encompassing a sequence within the center region of human NQO1. The exact sequence is proprietary.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWB
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

HumanMouse
Predicted Reactivity Rat, Pig, Rhesus Monkey, Bovine, Guinea pigRat (83%), Pig (92%), Rhesus Monkey (98%), Bovine (92%), Guinea pig (86%)
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
DHQU antibody
DIA4 antibody
DTD antibody
NMOR1 antibody
NMORI antibody
QR1 antibody
NQO1 antibody
phylloqui reductase antibody
dioxin-inducible 1 antibody
azoreductase antibody
NAD(P)H:Qui acceptor oxidoreductase type 1 antibody
qui
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Molecular Weight(MW) 31 kDa (note) (2)
Cellular Localization Cylasm

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded A549 xenograft, using NQO1 antibody at 1:100 dilution.

  • Application

    NQO1 antibody detects NQO1 protein by Western blot analysis. A. 50 µg mouse heart lysate/extract 12 % SDS-PAGE NQO1 antibody dilution: 1:500

  • Application

    Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 12% SDS PAGE diluted at 1:1000

Positive Control HeLa , HepG2 , mouse heart
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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