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NQO1 antibody , C-term Catalog Number：OM265893

點擊次數(shù)：58 發(fā)布時間：2024/9/24 15:06:26
 

Product Profile

Product Name NQO1 antibody , C-term
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, qui 1)This gene is a member of the NAD(P)H dehydrogenase (qui) family ａnd encodes a cylasmic 2-electron reductase. This FAD-binding protein forms homodimers ａnd reduces quis to hydroquis. This protein＇s enzymatic activity prevents the one electron reduction of quis that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, ａnd susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors ａnd is also associated with Alzheimer＇s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
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Immunogen 
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NQO1. The exact sequence is proprietary.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ICC/IFIHC-PWB
 
WB:1:500~1:2000
ICC/IF:1:100~1:500
IHC-P:1:50~1:200
Species Reactivity

HumanMonkeyMouseRat
Predicted Reactivity Rhesus MonkeyRhesus Monkey (100%)
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
DHQU antibody
DIA4 antibody
DTD antibody
NMOR1 antibody
NMORI antibody
QR1 antibody
NQO1 antibody
phylloqui reductase antibody
dioxin-inducible 1 antibody
azoreductase antibody
NAD(P)H:Qui acceptor oxidoreductase type 1 antibody
qui
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Molecular Weight(MW) 31 kDa (note) (4)
Cellular Localization Cylasm

Application

  • Application

    Sample (30 µg of whole cell lysate) A: Molt-4 B: Raji 12% SDS PAGE diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

  • Application

    NQO1 antibody [C2C3], C-term detects NQO1 protein at cylasm in human rectal carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human rectal carcinoma. NQO1 antibody [C2C3], C-term diluted at 1:500.

  • Application

    NQO1 antibody [C2C3], C-term detects NQO1 protein by western blot analysis. A. 50 µg mouse heart lysate/extract 12% SDS-PAGE NQO1 antibody [C2C3], C-term dilution: 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

  • Application

    NQO1 antibody [C2C3], C-term detects NQO1 protein by western blot analysis. A. 50 µg rat heart lysate/extract 12% SDS-PAGE NQO1 antibody [C2C3], C-term dilution: 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

  • Application

    Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NQO1 antibody at 1:200 dilution.

Positive Control Molt-4 , Raji , mouse heart , rat heart
Application Notes
WB:1:500~1:2000
ICC/IF:1:100~1:500
IHC-P:1:50~1:200

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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