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技術(shù)文章

GSTM1 [A4-H4] Catalog Number：OM627683

點(diǎn)擊次數(shù)：38 發(fā)布時(shí)間：2024/9/23 15:29:35
 

Product Profile

Product Name GSTM1 [A4-H4]
Antibody Type Primary Antibodies
Product description 
Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely alpha, zeta, theta, kappa, mu, pi, sigma ａnd omega, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human ａnd GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione ａnd function in the detoxification of carcinogens, environmental toxins ａnd products of oxidative stress.
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Immunogen 
Recombinant protein

Key Feature

Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications

WBICCFC
 
WB:1:500-1:2,000
IHC:1:100-1:500
FC:1:100-1:200
Species Reactivity

HumanMonkey
Concentration 2 mg/mL.

Target Information

Alternative Names
EC=2.5.1.18 antibody Glutathione S-transferase Mu 1 antibody GST class-mu 1 antibody GST HB subunit 4 antibody GST1 antibody Gstm1 antibody GSTM1-1 antibody GSTM1_HUMAN antibody GSTM1a-1a antibody GSTM1b-1b antibody GTH4 antibody GTM1 antibody H-B antibody LIVER AND FIBROBLAST GST1 antibody MU antibody MU-1 antibody
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Molecular Weight(MW) 26 kDa
Cellular Localization Cylasm.

Database Links

SwissProt ID P09488

Application

  • Application

    Fig1: Western blot analysis of GSTM1 on human GSTM1 recombinant protein using anti-GSTM1 antibody at 1/1,000 dilution.

  • Application

    Fig2: Western blot analysis of GSTM1 on different cell lysates using anti-GSTM1 antibody at 1/1,000 dilution. Positive control: Lane 1: Cos7 Lane 2: MCF-7 Lane 3: Jurkat Lane 4: Hela Lane 5: HL7702 Lane 6: HepG2

  • Application

    Fig3: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti-GSTM1 antibody. Counter stained with hematoxylin.

  • Application

    Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-GSTM1 antibody. Counter stained with hematoxylin.

  • Application

    Fig5: Flow cytometric analysis of Jurkat cells with GSTM1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).

Positive Control Human GSTM1 recombinant protein, Cos7, MCF-7, Jurkat, Hela, HL7702, HepG2, human rectum cancer tissue, human liver cancer tissue.
Application Notes
WB:1:500-1:2,000
IHC:1:100-1:500
FC:1:100-1:200

Additional Information

Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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