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聯(lián)系人：楊燕燕
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技術(shù)文章
Anti-GSTM1 antibody Catalog Number：OM642622
點擊次數(shù)：35 發(fā)布時間：2024/9/23 15:22:35
Product Profile
| Product Name | Anti-GSTM1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | GSTM1 |
|---|---|
| Gene Synonyms | More |
| Gene Full Name | glutathione S-transferase mu 1 |
| Gene Summary | Cytosolic ａnd membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cylasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta ａnd zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins ａnd products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 ａnd are known to be highly polymorphic. These genetic variations can change an individual＇s susceptibility to carcinogens ａnd toxins as well as affect the toxicity ａnd efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins ａnd carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] More |
| Molecular Weight(MW) | 26KD(Observed:55KD) |
| Cellular Localization | Cylasm |
Application
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WB
Western blot analysis using GSTM1 antibody against Cos7(1),Hela (2),Hepg2,A431(4) cell lysate.
-
IHC
Immunohistochemical analysis of paraffin-em
bedded liver cancer tissues using GSTM1 antibody with DAB staining. -
ICC/IF
Immunofluorescence analysis of C2C12 cells using GSTM1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500 |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
