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技術(shù)文章

NF-L antibody Catalog Number：OM265290

點(diǎn)擊次數(shù)：21 發(fā)布時間：2024/9/20 15:15:21
 

Product Profile

Product Name NF-L antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to 68kDa Neurofilament Light (neurofilament, light polypeptide)Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, ａnd heavy chains. Neurofilaments comprise the axoskeleton ａnd they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons ａnd dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) ａnd 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]
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Immunogen 
Recombinant protein encompassing a sequence within the center region of human 68kDa Neurofilament Light. The exact sequence is proprietary.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWB
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

Human
Predicted Reactivity Rhesus MonkeyRhesus Monkey (100%)
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
CMT1F antibody
CMT2E antibody
FLJ53642 antibody
NF-L antibody
NF68 antibody
NFL antibody
NEFL antibody
"neurofilament protein
light chain antibody"
neurofilament triplet L protein antibody
"neurofilament
light polypeptide 68kDa antibody"
68 kDa
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Molecular Weight(MW) 62 kDa (note)

Application

  • Application

    Sample (30 ug of whole cell lysate) A: PC-3 B: U87-MG C: SK-N-SH 7.5% SDS PAGE diluted at 1:10000

  • Application

    Immunohistochemical analysis of paraffin-embedded U87 xenograft, using 68kDa Neurofilament Light antibody at 1:500 dilution.

Positive Control PC-3 , U87-MG , SK-N-SH
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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