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Fibrinogen gamma antibody Catalog Number：OM253133

點擊次數(shù)：75 發(fā)布時間：2024/9/19 14:19:17
 

Product Profile

Product Name Fibrinogen gamma antibody
Antibody Type Primary Antibodies
Product description 
Rabbit polyclonal antibody to Fibrinogen gamma (fibrinogen gamma chain)The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
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Immunogen 
Recombinant protein encompassing a sequence within the center region of human Fibrinogen gamma. The exact sequence is proprietary.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ICC/IFIHC-PWB
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

HumanMouse
Predicted Reactivity Rat, Pig, Chicken, BovineRat (91%), Pig (88%), Chicken (81%), Bovine (88%)
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
FGG antibody
"fibrinogen
gamma polypeptide antibody"
fibrinogen gamma chain antibody
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Target Fibrinogen gamma
Molecular Weight(MW) 52 kDa (note) (3)
Cellular Localization Secreted

Application

  • Application

    Fibrinogen gamma antibody detects Fibrinogen gamma protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, ａnd the membrane was blotted with Fibrinogen gamma antibody diluted by 1:1000.

  • Application

    Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Fibrinogen gamma antibody at 1:200 dilution.

  • Application

    Fibrinogen gamma antibody detects Fibrinogen gamma protein by western blot analysis. Human plasma ａnd HepG2 conditioned medium were separated by 10% SDS-PAGE, ａnd the membrane was blotted with Fibrinogen gamma antibody diluted at 1:2000.

  • Application

    Fibrinogen gamma antibody detects Fibrinogen gamma protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Fibrinogen gamma antibody dilution: 1:250.

  • Application

    Fibrinogen gamma antibody detects Fibrinogen gamma protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10% SDS-PAGE, ａnd the membrane was blotted with Fibrinogen gamma antibody diluted at 1:1000.

Positive Control 293T , A431 , HeLa , HepG2 , human plasma , HepG2 sup. , Mouse plasma
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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