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技術(shù)文章

FIBG Antibody Catalog Number：OM278858

點(diǎn)擊次數(shù)：41 發(fā)布時(shí)間：2024/9/19 11:55:50
 

Product Profile

Product Name FIBG Antibody
Antibody Type Primary Antibodies
Product description 
FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia.1) Nowak-Gottl,U., Blood 114 (9), 1947-1953 (2009)
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Immunogen 
This FIBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human FIBG.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IFIHC-PWB
 
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml

Target Information

Gene Symbol FGG
Alternative Names
Fibrinogen gamma chain
FGG
Molecular Weight(MW) 52 kDa

Database Links

Entrez Gene 2266
Protein Accession P02679

Application

  • Application

    Confocal immunofluorescent analysis of FIBG Antibody with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

  • Application

    FIBG Antibody IHC analysis in formalin fixed ａnd paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody ａnd DAB staining.

  • Application

    Western blot analysis of FIBG Antibody in NCI-H460 cell line lysates (35ug/lane)

  • Application

    Western Blot at 1:4000 dilution + A431 whole cell lysate Lysates/proteins at 20 ug per lane.

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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