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技術(shù)文章

Rabbit anti-FGG polyclonal antibody - middle region Catalog Number:OM111723

點(diǎn)擊次數(shù):25 發(fā)布時(shí)間:2024/9/19 11:49:50
 

Product Profile

Product Name Rabbit anti-FGG polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen
The immunogen for anti-FGG antibody: synthetic peptide directed towards the middle region of human FGG

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

 
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHorseHumanMousePigRabbitZebra Fish

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol FGG
Gene Synonyms
-
Gene Full Name Fibrinogen gamma chain
Gene Summary
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
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Molecular Weight(MW) 46kDa
Sequence 437 amino acids

Database Links

Entrez Gene 2266
SwissProt ID P02679
Protein Accession NP_000500

Application

  • Immunohistochemistry

    Immunohistochemistry with Placenta tissue

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:1562500
    Positive Control: 721_B cell lysate

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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