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聯(lián)系人：楊燕燕
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技術(shù)文章
Rabbit anti-FGG polyclonal antibody - middle region Catalog Number：OM111725
點擊次數(shù)：22 發(fā)布時間：2024/9/19 11:48:58
Product Profile
| Product Name | Rabbit anti-FGG polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-FGG antibody: synthetic peptide directed towards the middle region of human FGG |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | BovineDogHorseHumanMousePigRabbitZebra Fish |
| Concentration | 1 mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | FGG |
|---|---|
| Gene Synonyms | |
| Gene Full Name | Fibrinogen gamma chain |
| Gene Summary | FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia.The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. More |
| Molecular Weight(MW) | 46kDa |
| Sequence | 437 amino acids |
Database Links
| Entrez Gene | 2266 |
|---|---|
| SwissProt ID | Q53Y18 |
| Protein Accession | NP_000500 |
Application
-
Western blot
2.5ug/ml
Positive Control: Human Live
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot ａnd store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
