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技術(shù)文章

FGG Antibody Catalog Number：OM278839

點(diǎn)擊次數(shù)：24 發(fā)布時(shí)間：2024/9/19 11:38:39
 

Product Profile

Product Name FGG Antibody
Antibody Type Primary Antibodies
Product description 
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in this protein lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia.1) Sie,M.P., Isaacs,A. J. Hypertens. 27 (7), 1392-1398 (2009)
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Immunogen 
This FGG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human FGG.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

FACSIHC-PWB
 
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml

Target Information

Gene Symbol FGG
Alternative Names
Fibrinogen gamma chain
FGG
Molecular Weight(MW) 52 kDa

Database Links

Entrez Gene 2266
Protein Accession P02679

Application

  • Application

    Flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

  • Application

    Western blot analysis in human blood plasma cell line lysates (35ug/lane).

  • Application

    FGG Antibody (RB18714) IHC analysis in formalin fixed ａnd paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody ａnd DAB staining.

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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