企業(yè)檔案
- 會(huì)員類型：免費(fèi)會(huì)員
- 工商認(rèn)證： 【已認(rèn)證】
- 最后認(rèn)證時(shí)間：
- 法人：
- 注冊(cè)號(hào)：
- 企業(yè)類型：生產(chǎn)商
- 注冊(cè)資金：人民幣萬(wàn)
聯(lián)系我們
聯(lián)系人：楊燕燕
熱門(mén)標(biāo)簽
友情鏈接
- 保健按摩服務(wù)：
- 在線濁度儀
- 開(kāi)展各類檢測(cè)業(yè)務(wù)各類檢測(cè)設(shè)備的
- 北京小池文化傳媒有限公司
- 標(biāo)準(zhǔn)品
- 北京小池文化傳媒有限公司
- AB/施耐德/
- 伺服電機(jī)驅(qū)動(dòng)器
- 水泥試驗(yàn)儀器
- 調(diào)節(jié)閥
- 水泵
- 無(wú)線氣象站
- 太倉(cāng)柴油批發(fā)
- ,石油儀器
- 深圳市賽德力檢測(cè)設(shè)備有限公司
- 技術(shù)轉(zhuǎn)讓
- 美國(guó)FLUKE工業(yè)測(cè)試儀器
- 測(cè)硫儀
- ELISA免費(fèi)代測(cè)
- 磁盤(pán)陣列柜
技術(shù)文章
Gab1 Antibody Catalog Number：OM233623
Product Profile
| Product Name | Gab1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1AT1979 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB~~1:1000: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
Target Information
| Alternative Names | More |
|---|---|
| Molecular Weight(MW) | 76616 Da |
| Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) ａnd the insulin receptor (INSR) |
| Tissue Specificity | This Gab1 antibody is generated from mice immunized with a GST fusion protein encoding full length human GAB1. |
Database Links
| Entrez Gene | 2549 |
|---|
Application
-
Application
Wild-type (+/+) ａnd Gab1-/- (-/-) cells were heat shocked (HS) at 42擄C for 1 h or irradiated with UV-B light (400 J/m2) ａnd then incubated at 37? for 1 h. Cell lysates were prepared ａnd subjected to immunoprecipitation (IP) with an anti-JNK2 antibody. The immunoprecipitates were resolved by SDS- PAGE ａnd immunoblotted (IB) with anti-Gab1 antibody. Data courtesy of Dr. GS Feng at The Burnham Institute.
-
Application
Rescue of the JNK pathway by expression of wild-type Gab1 in Gab1-/- cells. Gab1-/- cells were transiently transfected with 1, 2, or 4 of the expression construct for human Gab1 cDNA, using the GenePORTER 2 transfection reagent (Gene Therapy Systems Inc.). After incubation, the cells were irradiated with UV-B light at 400 J/m2 or left untreated. Exogenous expression of Gab1 in transfected cells was confirmed by anti-Gab1 immunoblot analysis with wild-type cells as positive control. +/+, wild-type cells; -/-, Gab1-/- cells. (Mol. Cell. Biol. 2004 Feb 15;24(4):1531-1539)
| Application Notes | WB~~1:1000: |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high ａnd low pH buffers ａnd neutralized immediately, followed by dialysis against PBS. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
