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技術(shù)文章

Phospho-Gab1-Y627 Antibody Catalog Number:OM217323

點(diǎn)擊次數(shù):25 發(fā)布時(shí)間:2024/9/14 13:45:48
 

Product Profile

Product Name Phospho-Gab1-Y627 Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

DB

 
DB~~1:100~500:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Alternative Names
GAB1
GRB2-associated-binding protein 1
GRB2-associated binder 1
Growth factor receptor bound protein 2-associated protein 1
More 
Molecular Weight(MW) 76616 Da
Function
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR)
Tissue Specificity This Phospho-Gab1-Y627 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 612~641 amino acids surrounding Y627 of human Gab1.

Database Links

Entrez Gene 2549

Application

  • Application

    Dot blot analysis of Phospho-Gab1-Y627 Antibody and Gab1 Non Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Application Notes
DB~~1:100~500:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
 

原創(chuàng)作者:上海篤瑪生物科技有限公司

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