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技術(shù)文章

GAB1 antibody Catalog Number：OM253807

點(diǎn)擊次數(shù)：25 發(fā)布時(shí)間：2024/9/14 13:39:58
 

Product Profile

Product Name GAB1 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to GAB1 (GRB2-associated-binding protein 1)The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis ａnd plays a central role in cellular growth response, transformation ａnd apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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Immunogen 
Recombinant protein encompassing a sequence within the center region of human GAB1. The exact sequence is proprietary.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWB
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

HumanMouse
Predicted Reactivity Rat, Rhesus Monkey, BovineRat (86%), Rhesus Monkey (100%), Bovine (93%)
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
GAB1 antibody
GRB2-associated binder 1 antibody
growth factor receptor bound protein 2-associated protein 1 antibody
GRB2-associated-binding protein 1 antibody
GRB2-associated binding protein 1 antibody
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Molecular Weight(MW) 77 kDa (note) (2)

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using GAB1 antibody at 1:500 dilution.

  • Application

    Sample (30 µg of whole cell lysate) A: JC B: BCL-1 7.5% SDS PAGE diluted at 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

  • Application

    Sample (30 µg of whole cell lysate) A: HCT116 B: MCF-7 7.5% SDS PAGE diluted at 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Positive Control HCT116 , MCF-7 , JC , BCL-1 , *C2C12
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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