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技術(shù)文章

Mapk8 Antibody Catalog Number：OM285161

點(diǎn)擊次數(shù)：29 發(fā)布時間：2024/9/12 15:13:15
 

Product Profile

Product Name Mapk8 Antibody
Antibody Type Primary Antibodies
Product description 
Mapk8 responds to activation by environmental stress ａnd pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 ａnd ATF2 ａnd thus regulates AP-1 transcriptional activity. In T-cells, JNK1 ａnd JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity).1) Sherrin, T., et al. J. Neurosci. 30(40):13348-13361(2010)
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Immunogen 
This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB
 
For WB starting dilution is: 1:1000:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol Mapk8
Alternative Names
Mitogen-activated protein kinase 8
MAP kinase 8
MAPK 8
Stress-activated protein kinase JNK1
c-Jun N-terminal kinase 1
Mapk8
Jnk1
Prkm8
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Molecular Weight(MW) 44 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Rat

Database Links

Entrez Gene 26419
Protein Accession Q91Y86

Application

  • Application

    Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Application Notes
For WB starting dilution is: 1:1000:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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